C57BL/6JGpt-Nr1h4em6Cd18703/Gpt
Nr1h4-KO|Strain NO.T012640
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Nr1h4em6Cd18703/Gpt |
| Strain Number: | T012640 |
| Official Symbol: | Nr1h4 |
| Strain Strategy: | T012640. Nr1h4-KO strain info.pdfT012640.Nr1h4 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | nuclear receptor subfamily 1, group H, member 4 |
| Also Known As: | AI957360,Fxr,HRR1,RIP14,Rxrip14 |
| NCBI Number: | 20186 |
| MGI Number: | 1352464 |
| Chromosome: | 10 |
| Deletion (size): | -18703bp |
| Research Areas: | Metabolic research,adipose tissue,Protein metabolism,homeostasis/metabolism,Lipid Metabolism,Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,Tumor research,nervous system,behavior/neurological,Physiological system,cardiovascular system,skeleton,digestive/alimentary system,liver/biliary system,endocrine/exocrine glands,hematopoietic system,Cell biology,Cell death,cellular,Cell localization,cell nucleus,Molecular biology,Signal Transduction,DNA transcription,DNA binding protein,Lipid binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T012640.Nr1h4 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Chenodeoxycholic acid modulates cholestatic niche through FXR/Myc/P-selectin axis in liver endothelial cells. Nat Commun (2025) |
| Gene Family: | Nuclear hormone receptors |